Jozef Stefan Institute, Ljubljana, Slovenia. Provides recent advances in the role of proteases under physiological and pathological conditions. Reviews contributions in biochemistry, molecular biology, medicine, agriculture, and ecology. Shows how protease structures are essential in drug design. For graduate students and researchers.
List of contributors
vii
Peptidases: a view of classification and nomenclature
1
(12)
Alan J. Barrett
Carboxypeptidases
13
(22)
Josep Vendrell
Francesc X. Aviles
Signal peptidases
35
(10)
Mark O. Lively
Christopher M. Ashwell
Proteasomes
45
(14)
A. Jennifer Rivett
Grant G. F. Mason
Cathepsin E and cathepsin D
59
(14)
Kenji Yamamoto
Cell-associated metalloproteinases
73
(22)
Gary D. Johnson
Judith S. Bond
Proteinases in Parasites
95
(14)
Juan Jose Cazzulo
Cell-surface proteases in cancer
109
(16)
Lisa L. Demchik
Bonnie F. Sloane
Insect proteinases
125
(24)
Gerald Reeck
Brenda Oppert
Michael Denton
Michael Kanost
James Baker
Karl Kramer
Alzheimer's disease and proteinases
149
(10)
Shoichi Ishiura
Calpains: structure and function of the calpain super family
159
(16)
Yasuko One
Hiroyuki Sorimachi
Koichi Suzuki
Arg-gingipain and Lys-gingipain: a novel class of cysteine proteinases
175
(10)
Kenji Yamamoto
Tomoko Kadowaki
Kuniaki Okamoto
Proteinases in apoptosis
185
(10)
Masanori Tomioka
Seiichi Kawashima
Caspases: cytokine activators and promoters of cell death
195
(16)
Guy S. Salvesen
Henning R. Stennicke
Lysosomal cysteine proteinases: Structure and regulation
211
(14)
Vito Turk
Gregor Guncar
Dusan Turk
Subject index
225
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