Protein Degradation Series, 4 Volume Set

Nobel prize content by Nobel prize winners: The essential role of protein degradation as a regulatory switch in cell physiology has been honored by the 2004 Nobel prize in Chemistry to Aaron Ciechanover, editor of the series, and Avram Hershko, the author of the opening chapter of volume 1. Broad coverage: Four volumes with more than 50 contributions in total cover all aspects of protein degradation. Each individual volume highlights a different aspect of the field; all four volumes together provide the most comprehensive reference on protein degradation available. Unmatched expertise: Editors and authors comprise virtually all the top scientists in the field, including the pioneers of protein degradation research.

John Mayer obtained his MS and PhD degrees from the University of Birmingham (UK). He is currently serving as Professor of Biochemistry at the School of Biomedical Sciences at Nottingham University.
For the past 30 years, he has investigated intracellular proteolysis and particularly the ubiquitin/proteasome system. Presently, he is particularly interested in intracellular proteolysis in relation to neurodegenerative illnesses.

Aaron Ciechanover obtained his MD from the Hebrew University in Jerusalem (Israel), and his PhD from the Technion-Israel Institute of Technology in Haifa, where he is presently serving as Professor of Biochemistry. Professor Ciechanover is known for his discovery of the first ubiquitin system mutant cell, demonstrating the role of the ubiquitin-proteasome proteolytic system in protein degradation in vivo. In 2004, he has received the Nobel Prize in Chemistry for his ground-breaking work on the ubiquitin-proteasome system.

Martin Rechsteiner is Professor of Biochemistry at the University of Utah in Salt Lake City (USA). He is interested in the proteasome component of the ubiquitin-proteasome pathway. He has identified several key regulators of proteasome function and is currently working on their structural and functional elucidation.