Protein Targeting, Transport, and Translocation

This book presents an in-depth overview on the topic of protein synthesis, covering all areas of protein science, including protein targeting, secretion, folding, assembly, structure, localization, quality control, degradation, and antigen presentation. Chapters also include sections on the history of the field as well as summary panels for quick reference. Numerous color illustrations complement the presentation of material. This book is an essential reference for anyone in biochemistry and protein science, as well as an excellent textbook for advanced students in these and related fields. Key Features * Basic principles and techniques * Targeting adn sorting sequences * Protein export in bacteria * Membrane protein integration into ER and bacterial membranes * Protein translocation across the ER * Disulfide bond formation in prokaryotes and eukaryotes * Quality control in the export pathway * Import of proteins into organelles * The secretory pathway * Vesicular transport * Spectacular color throughout

James C.A. Bardwell, Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor Jason H. Brickner, Department of Biochemistry and Biophysics, University of California, San Francisco Minyong Chen, Department of Chemistry, The Ohio State University, Columbus Ross E. Dalbey, Department of Chemistry, Ohio State University Vincent Dammai, Section of Molecular Biology, Division of Biology, University of California, San Diego Arnold J.M. Driessen, Department of Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen Benjamin Glick, Department of Molecular Genetics and Cell Biology, Cummings Life Science Center, University of Chicago Dirk Gorlich, Zentrum fur Molekulare Biologie Universitat Heidelberg Todd R. Graham, Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee Nora G. Haigh, Department of Medical Biochemistry and Genetics, Texas A&M University System Health Science Center Partha Hazra, Section of Molecular Biology, Division of Biology, University of California Lisa Heins, Botanisches Institut der Christian Albrechts Universitat Stefan Jakel, Zentrum fur Molekulare Biologie, Universitat Heidelberg Arthur E. Johnson, Department of Medical Biochemistry and Genetics, Texas A&M University System Health Science Center Zlatka Kostova, Institut fur Biochemie der Universitat Stuttgart Andreas Kuhn, University of Hohenheim, Institute for Microbiology and Molecular Biology Soojin Lee, Section of Molecular Biology, Division of Biology, University of California, San Diego Tommy Nilsson, Cell Biology Programme, European Molecular Biology Laboratory, Heidelberg, Germany Steven F. Nothwehr, Division of Biological Sciences, University of Missouri, Columbia Joachim Ostermann, McGill University, Department of Anatomy and Cell Biology Nikolaus Pfanner, Institut fur Biochemie und Molekularbiologie Universitat Freiburg Thorsten Prinz, Institut fur Biochemie und Molekularbiologie Universitat Freiburg James Reigembal, Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor Colin Robinson, University of Warwick, Department of Biological Sciences, Coventry Carmela Sidrauski, Department of Biochemistry and Biophysics, University of California, San Francisco Jurgen Soll, Botanisches Institut der Universitat Kiel, Germany Martin Spiess, Department of Biochemistry, Biozentrum, University of Basel, Switzerland Tobias Stauber, Cell Biology Programme, European Molecular Biology Laboratory, Heidelberg, Germany Ivet Suriapranata, Section of Molecular Biology, Division of Biology, University of California, San Diego Suresh Subramani, Department of Biology, University of California, San Diego Kaye N. Truscott, Institut fur Biochemie und Molekularbiologie Universitat Freiburg, Germany Chris van der Does, Department of Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute, The Netherlands Gunnar von Heijne, Department of Biochemistry, Arrhenius Laboratory, Stockholm University, Sweden Peter Walter, Department of Biochemistry and Biophysics, University of California, San Francisco Martin Wiedmann, Cellular Biochemistry and Biophysics Program, Memorial Sloan-Kettering Cancer Center, New York Dieter H. Wolf, Institut fur Biochemie, Universitat Stuttgart, Germany