Quantitative Imaging Tools for Lung Cancer

Cancer Research and Prevention Monographpresents chapters written by leading clinical researchers in the field of lung cancer, where high resolution 3-D imaging technology appears to hold the greatest near-term promise. This book has contributions from recognized experts in CAD, medical information technology systems, regulatory procedure, x-ray standards development, and clinical trial design. These expert contributors discuss the current state of the art and provide a road map for directing further research in lung cancer and other diseases.

James L. Mulshine, MD, is a Professor of Internal Medicine, Associate Provost of Research and Vice President, Rush University Medical Center in Chicago, Illinois.?In this position, Dr. Mulshine is the primary academic officer responsible for managing research activities at Rush University Medical School. He is an internationally recognized expert on lung cancer.?Over the last few years, Dr. Mulshine has been working with a range of organizations to accelerate the use of high resolution spiral CT in the quantitative evaluation of drug response for early lung cancer.

Contributors	p. vii
Preface	p. ix
Incorporating Imaging into Drug Development: An Industry Perspective	p. 1
Advances in Lung Cancer Treatment	p. 17
Quantitative Imaging in CT Lung Cancer Drug Development and Evaluation	p. 39
Volumetric CT Imaging for Response Assessment in Lung Cancer: A Platform for Translational Research	p. 53
Emerging Radiological Software Standards and Development Technologies: Impact on Clinical Translation and Trials	p. 67
Statistical Considerations Underlying Therapeutic Response Criteria for Lung Cancer: Multislice CT Scanners and CAD Algorithms for Volumetric Assessment	p. 95
Programs Supporting Quantitative Imaging in Biomedicine at the National Institute of Standards and Technology	p. 111
Evolving Imaging Resources: Public Access Databases	p. 123
Biomedical Imaging Archive Network	p. 131
Developing CT Image-Processing Tools to Accelerate Progress in Lung Cancer Drug Development	p. 141
Index	p. 155
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Quantitative Imaging Tools for Lung Cancer Drug Assessment

Summary

Author Biography

Table of Contents

Supplemental Materials