Quantitative Methods in Neuroscience A Neuroanatomical Approach

Stereology is a valuable tool for scientists, allowing them to make 3-Dreconstructions of the brain from 2-D data (as usually obtained from PET or MRIscans). Such 3-D reconstructions allow a far greater understanding of brainfunction. However, in carrying out such reconstructions, often based on limitedor incomplete data, there is always a risk of experimenter bias. An importantfunction of stereology is to eliminate bias in the data. With many of the majorneuroscience journals now insisting that data be presented in this way, there isa greater need than ever for neuroscientists to understand 'unbiased'quantitative methods, such as those offered by stereology.'Quantitative methods in neuroscience' is a cookbook of stereological methodswritten especially for neuroscientists. It provides clear and accessible adviceabout when and when not to use stereology. Throughout the book, the emphasis ison practical guidance, rather than discussions and formulae. Written by leadingscientists in the field of stereology, the book will be a valuable introductionto these methods for neuroscientists, and all those involved in development ofnew drug programmes.