Randomised Response-Adaptive Designs in Clinical Trials

Response-adaptive designs, which aim to reduce the number of patients receiving inferior treatments, are becoming increasingly popular in Phase III clinical trials. Written by leading experts, Response-Adaptive Designs in Clinical Trials provides an overview of the growing research in this area, presents up-to-date methodology, and includes all necessary background material on adaptive clinical trials. Illustrating methods with numerous real-world examples from recent clinical trials, the book offers practical guidelines for applying these methods in the field, includes supporting software available for download, and explores future research directions.