Redox-genome Interactions in Health and Disease

At the nexus of breakthroughs in molecular genetics and recent findings in redox biology, Redox-Genome Interactions in Health and Disease examines the dynamics governing cellular redox states and brings together the evidence linking oxidative stress and redox modulation with the pathogenesis of numerous monogenetic and polygenetic diseases. It characterizes the redox state in terms of its impact on signaling, gene expression, and progressive damage manifested in apoptosis, nucleic acid modification, and tumor proliferation. It also investigates the role of oxidative stress and imbalance in diabetes mellitus, cystic fibrosis, hypertension, colon cancer, Alzheimer's disease, and many other diseases.