Note: Supplemental materials are not guaranteed with Rental or Used book purchases.
- ISBN: 9780849333712 | 0849333717
- Cover: Hardcover
- Copyright: 11/1/2005
Practicing evidenced-based medicine some 25 centuries ago, Hippocrates proclaimed "Let food be thy medicine and medicine be thy food." This advice parallels the common American saying, "You are what you eat," and is supported by a National Institute of Health recommendation to consume as many as eight servings of fruits and vegetables daily to prevent common diseases.One of the most therapeutically significant components found in food is the polyphenol resveratrol. First described in Ayurvedic medicine 5000 years ago as a cardiotonic, resveratrol is found in several fruits and vegetables including grapes, peanuts, cranberries, blueberries, mulberries, and jackfruit. A favorite and rich source of resveratrol is red wine.Resveratrol in Health and Disease draws on the expertise of an international panel, representing a cross-section of nutrition-related disciplines, to examine the effects and properties of this legendary nutrient. It explores research that examines a wide range of purported healing and preventive powers:· Cardioprotective agent· Antitumor agent· Angiogenesis inhibitor· Antioxidant· Radioprotective agent· Phytoestrogen source· Antifungal and antibacterial agent· Neuroprotective agent· Modulator of immune system· Anti-inflammatory agentReviewing recent literature, these pages explore the pharmacokinetics and metabolism of resveratrol, consider its molecular targets, and look at its role in modulating gene expression, as well as its impact on the mechanism of apoptosis and cell signaling pathways.Considering the prohibitive costs of modern medicine, the need for readily available products that are safe and efficacious is critical. Consequently, Resveratrol in Health and Disease may well find its own place in history by providing scientists, clinicians, herbalogists, naturopaths, and those they serve, with the first comprehensive overview of this long-lauded tonic.
Chapter 1 Resveratrol: A Polyphenol for All Seasons | 1 | (16) | |||
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Chapter 2 Sources and Chemistry of Resveratrol | 17 | (16) | |||
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Chapter 3 Resveratrol as an Antioxidant | 33 | (24) | |||
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Chapter 4 Resveratrol as an Antiproliferative Agent for Cancer | 57 | (28) | |||
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58 | (1) | |||
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Chapter 5 Mechanism of Apoptosis by Resveratrol | 85 | (20) | |||
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85 | (3) | |||
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87 | (1) | |||
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88 | (5) | |||
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98 | (1) | |||
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98 | (7) | |||
Chapter 6 Resveratrol as Inhibitor of Cell Survival Signal Transduction | 105 | (14) | |||
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106 | (1) | |||
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Chapter 7 Resveratrol as Inhibitor of Cell Cycle Progression | 119 | (14) | |||
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120 | (1) | |||
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Chapter 8 Molecular Targets of Resveratrol: Implications to Health and Disease Prevention | 133 | (16) | |||
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133 | (3) | |||
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136 | (7) | |||
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143 | (1) | |||
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144 | (5) | |||
Chapter 9 Resveratrol as an Angiogenesis Inhibitor | 149 | (18) | |||
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151 | (8) | |||
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Chapter 10 Resveratrol Modulation of Gene Expression: The Role of Transcription Factors | 167 | (26) | |||
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Chapter 11 Modulation of Gene Expression by Resveratrol | 193 | (22) | |||
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195 | (4) | |||
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Chapter 12 Resveratrol and Prostaglandin Biosynthesis | 215 | (18) | |||
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Chapter 13 Resveratrol as an Inhibitor of Carcinogenesis | 233 | (152) | |||
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237 | (3) | |||
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337 | (24) | |||
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363 | (1) | |||
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Chapter 14 Resveratrol as an Antitumor Agent In Vivo | 385 | (14) | |||
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386 | (7) | |||
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Chapter 15 Resveratrol as a Sensitizer to Apoptosis-Inducing Stimuli | 399 | (24) | |||
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400 | (3) | |||
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408 | (5) | |||
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Chapter 16 Resveratrol as a Radio-Protective Agent | 423 | (16) | |||
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432 | (1) | |||
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Chapter 17 Resveratrol as a Phytoestrogen | 439 | (26) | |||
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439 | (2) | |||
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441 | (15) | |||
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442 | (24) | |||
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Chapter 18 Resveratrol as an Antibacterial Agent | 465 | (10) | |||
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Chapter 19 Resveratrol as an Antifungal Agent | 475 | (24) | |||
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477 | (4) | |||
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481 | (5) | |||
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488 | (11) | |||
Chapter 20 Protective Effects of Resveratrol in Age-Related Neurodegenerative Diseases and Gene Regulatory Action | 499 | (20) | |||
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499 | (4) | |||
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503 | (2) | |||
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505 | (2) | |||
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Chapter 21 Protective Effects of Resveratrol against Ischemia-Reperfusion | 519 | (20) | |||
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Chapter 22 Resveratrol as Cardioprotective Agent: Evidence from Bench and Bedside | 539 | (18) | |||
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550 | (7) | |||
Chapter 23 Immunomodulation by Resveratrol | 557 | (20) | |||
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559 | (1) | |||
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561 | (10) | |||
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Chapter 24 Biological Effects of Cis- Versus Trans-Resveratrol | 577 | (24) | |||
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577 | (2) | |||
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580 | (8) | |||
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586 | (2) | |||
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588 | (4) | |||
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594 | (7) | |||
Chapter 25 Resveratrol as an Antiinflammatory Agent | 601 | (18) | |||
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605 | (7) | |||
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Chapter 26 Neuroprotective Effects of Resveratrol | 619 | (12) | |||
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627 | (4) | |||
Chapter 27 Pharmacokinetics and Metabolism of Resveratrol | 631 | (12) | |||
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632 | (2) | |||
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634 | (4) | |||
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638 | (1) | |||
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639 | (2) | |||
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641 | (2) | |||
Index | 643 |
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The Used, Rental and eBook copies of this book are not guaranteed to include any supplemental materials. Typically, only the book itself is included. This is true even if the title states it includes any access cards, study guides, lab manuals, CDs, etc.