The Rise and Fall of Animal Experimentation Empathy, Science, and the Future of Research

Every year, hundreds of millions of animals are used in the service of biomedical research, despite the risk of extreme cruelty to these animal subjects. The expansion of the pharmaceutical industry and university research funding rapidly normalized its practice. What exactly are these experiments supposed to achieve from the scientific point of view and how effective are they? Working scientists answer these questions by saying that their research is absolutely necessary if we are to develop new therapies for human diseases. But is this really the case?

Written by a scientist with over 40 years of laboratory experience, The Rise and Fall of Animal Experimentation critically examines this assumption and asks whether it is true that animal-based research achieves its aims and, if so, how often this occurs and if there are alternatives to performing animal-based science. The book takes readers through the history of animal experimentation: its early beginnings in antiquity, how it advanced in the seventeenth century during the Scientific Revolution until the present day, and explores the diverse scientific, theological, and philosophical influences that formed the basis for these ideas about animal-based science. Referencing developments in various fields including stem cell biology, genetic sequencing, and live imaging, the book describes the scientific advancements that bring the value of animal experimentation into question and encourages biomedical research to consider more anthropocentric paradigms that reflect the entire spectrum of human diversity.

Richard J. Miller is Emeritus Professor at Northwestern University. He obtained his PhD from Cambridge University in 1975. Following a year working for the Burroughs-Wellcome Fund, he joined the faculty of the Pharmacology and Physiology department at the University of Chicago in 1976, where he earned the title of the William Mabie Professor of Pharmacology. In 2000, he became a member of the faculty in the Department of Pharmacology at Northwestern University's Feinberg School of Medicine as the Alfred Newton Richards Professor of Pharmacology, where he is an emeritus today.

Prologue: The Seminar

Chapter 1: Greek Awakenings
Chapter 2: Circular Arguments
Chapter 3: Mapping Humanity
Chapter 4: Fear and Trembling
Chapter 5: The Modern Prometheus
Chapter 6: I Want to be Your Dog
Chapter 7: Not Just Kids
Chapter 8: The Cloud Cap'd Towers

Bibliography
Index