Quantitative Evaluation of HIV Prevention

Yale Univ., New Haven, CT. Addresses the quantitative evaluation of HIV prevention programs. Describes quantitative approaches with an emphasis on statistical methods. Also presents articles discussing AIDS policy modeling, forecasting, infectivity and disease progression, and risky behavior.

Foreword

ix

Donald L. Thomsen, Jr.

Introduction

1

(12)

Edward H. Kaplan

Ron Brookmeyer

Part I: Evaluating HIV Prevention Programs: Context and Concepts

Overview of HIV Prevention Programs in Developing Countries

13

(19)

Michael H. Merson

Julia M. Dayton

Implications of Economic Evaluations for National HIV Prevention Policy Makers

32

(23)

David R. Holtgrave

Steven D. Pinkerton

Statistical Issues in HIV Prevention

55

(24)

Ron Brookmeyer

Epidemiological Issues in the Evaluation of HIV Prevention Programs

79

(18)

Nancy S. Padian

Stephen C. Shiboski

Part II: Cost-Effectiveness and Resource Allocation

Difficult Choices, Urgent Needs: Optimal Investment in HIV Prevention Programs

97

(21)

Margaret L. Brandeau

Methadone Treatment as HIV Prevention: Cost-Effectiveness Analysis

118

(25)

Harold Pollack

Costs and Benefits of Imperfect HIV Vaccines: Implications for Vaccine Development and Use

143

(32)

Douglas K. Owens

Donna M. Edwards

Ross D. Shachter

Part III: Case Studies

Harm Reduction in Rome: A Model-Based Evaluation of Its Impact on the HIV-1 Epidemic

175

(14)

Massimo Arca

Teresa Spadea

Giulia Cesaroni

Marina Davoli

Annette D. Verster

Carlo A. Perucci

Evaluating Israel's Ethiopian Blood Ban

189

(13)

Edward H. Kaplan

Feeding Strategies for Children of HIV-Infected Mothers: Modeling the Trade-Off Between HIV Infection and Non-HIV Mortality

202

(21)

James G. Kahn

Elliot Marseille

Joseph Saba

Part IV: New Methods for New Problems

Design of HIV Trials for Estimating External Effects

223

(18)

Tomas Philipson

Estimation of Vaccine Efficacy for Prophylactic HIV Vaccines

241

(19)

Ira M. Longini, Jr.

Michael G. Hudgens

M. Elizabeth Halloran

Health Policy Modeling: Epidemic Control, HIV Vaccines, and Risky Behavior

260

(30)

Sally Blower

Katia Koelle

John Mills

Development and Validation of a Serologic Testing Algorithm for Recent HIV Seroconversion

290

(15)

Glen A. Satten

Robert S. Janssen

Susan Stramer

Michael P. Busch

Issues in Quantitative Evaluation of Epidemiologic Evidence for Temporal Variability of HIV Infectivity

305

(26)

Stephen C. Shiboski

Nancy S. Padian

Index

331

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Quantitative Evaluation of HIV Prevention Programs

Summary

Table of Contents

Supplemental Materials