Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism

, by Favus, Murray J.; Christakos, Sylvia; Goldring, Steven R.; Hendy, Geoffrey N.; Holick, Michael F.

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ISBN: 9780397517633 | 0397517637
Cover: Paperback
Copyright: 6/1/1996

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Supplemental Materials

Contributing Authors

(6)

The American Society for Bone and Mineral Research

xvii

(2)

John G. Haddad, Jr.

Gideon A. Rodan

Preface to the First Edition

xix

(2)

Murray J. Favus

Preface to the Third Edition

xxi

(2)

Murray J. Favus

Acknowledgments

xxiii

Section I. Anatomy and Biology of Bone Matrix and Cellular Elements

(38)

1. Anatomy and Ultrastructure of Bone

(8)

Roland E. Baron

2. Osteoblast Cell Biology -- Lineage and Functions

(5)

J. Edward Puzas

3. Bone-Resorbing Cells

(8)

Gregory R. Mundy

4. Bone Matrix Proteins and the Mineralization Process

(5)

John D. Termine

Pamela Gehron Robey

5. Regulation of Bone Remodeling

(6)

Ernesto Canalis

6. The Osteoblast Lineage--Embryologic Origins and the Differentiation Sequence

(6)

Jane E. Aubin

Arnold Kahn

Section II. Calcium, Magnesium, Phosphorus Homeostasis and Physiology, and Biochemistry of Calcium Regulating Hormones

(50)

7. Calcium, Magnesium and Phosphorus: Intestinal Absorption

(8)

Neil A. Breslau

8. Calcium, Magnesium and Phosphorus: Renal Handling and Urinary Excretion

(8)

Neil A. Breslau

9. Mineral Balance and Homeostasis

(6)

Arthur E. Broadus

10. Synthesis, Circulating Heterogeneity, and Metabolism of Parathyroid Hormone

(5)

Gino V. Segre

Edward M. Brown

11. Parathyroid Hormone: Mechanism of Action

(3)

Henry M. Kronenberg

12. Parathyroid-Hormone-Related Protein

(3)

Gordon J. Strewler

Robert A. Nissenson

13. Vitamin D: Photobiology, Metabolism, Mechanism of Action and Clinical Applications

(8)

Michael F. Holick

14. Calcitonin

(9)

Leonard J. Deftos

Section III. Clinical Evaluation of Bone and Mineral Disorders

(86)

15. History and Physical Examination

(2)

Peter M. Sklarin

Dolores M. Shoback

16. Blood, Calcium, Phosphorus, and Magnesium

(3)

Anthony A. Portale

17. Parathyroid Hormone and Calcitonin

(9)

Lawrence E. Mallette

Robert F. Gagel

18. Parathyroid-Hormone-Related Protein Assays

105

(4)

William J. Burtis

19. Vitamin D Metabolites

109

(5)

Thomas L. Clemens

John S. Adams

20. Biochemical Markers of Bone Turnover

114

(5)

David R. Eyre

21. Radiologic Evaluation of Bone Mineral in Children

119

(15)

Richard M. Shore

Andrew K. Poznanski

22. Scintigraphy in Metabolic Bone Disease

134

(8)

David C. Wang

Sambasiva R. Kottamasu

Kastytis C. Karvelis

23. Bone Density Measurement and the Management of Osteoporosis

142

(10)

C. Conrad Johnston, Jr.

Charles W. Slemenda

L. Joseph Melton III

24. Radiology of Osteoporosis and Other Metabolic Bone Diseases

152

(13)

Harry K. Genant

25. Bone Biopsy and Histomorphometry in Clinical Practice

165

(3)

Robert R. Recker

26. Molecular Diagnosis of Bone and Mineral Disorders

168

(9)

Robert F. Gagel

Gilbert J. Cote

Section IV. Disorders of Serum Minerals

177

(71)

27. Hypercalcemia: Pathogenesis, Clinical Manifestations, Differential Diagnosis, and Management

177

(4)

Elizabeth Shane

28. Primary Hyperparathyroidism

181

(6)

John P. Bilezikian

29. Familial Hyperparathyroid Syndromes

187

(3)

Hunter Heath III

Maurine R. Hobbs

30. Familial Hypocalciuric Hypercalcemia

190

(2)

Stephen J. Marx

31. Tertiary Hyperparathyroidism and Refractory Secondary Hyperparathyroidism

192

(6)

Susan C. Galbraith

L. Darryl Quarles

32. Humoral Hypercalcemia of Malignancy

198

(5)

Andrew F. Stewart

33. Hypercalcemia in Hematologic Malignancies and in Solid Tumors Associated with Extensive Localized Bone Destruction

203

(3)

Gregory R. Mundy

34. Hypercalcemia Due to Granuloma-Forming Disorders

206

(3)

John S. Adams

35. Hypercalcemic Syndromes in Infants and Children

209

(4)

Craig B. Langman

36. Miscellaneous Causes of Hypercalcemia

213

(4)

Kai H. Yang

Andrew F. Stewart

37. Hypocalcemia: Pathogenesis, Differential Diagnosis, and Management

217

(3)

Elizabeth Shane

38. Hypoparathyroidism

220

(3)

David Goltzman

David E. C. Cole

39. Parathyroid Hormone Resistance Syndromes

223

(5)

Michael A. Levine

40. Neonatal Hypocalcemia

228

(2)

Thomas O. Carpenter

41. Miscellaneous Causes of Hypocalcemia

230

(4)

Karl L. Insogna

Andrew F. Stewart

42. Magnesium Depletion and Hypermagnesemia

234

(4)

Robert K. Rude

43. Hyperphosphatemia and Hypophosphatemia

238

(10)

Keith A. Hruska

John Connolly

Section V. Metabolic Bone Diseases

248

(114)

Section V. Introduction

248

(1)

Sundeep Khosla

Michael Kleerekoper

44. Epidemiology of Osteoporosis

249

(4)

Richard D. Wasnich

45. Pathogenesis of Postmenopausal Osteoporosis

253

(1)

Robert P. Heaney

46. Physical Activity and Regulation of Bone Mass

254

(2)

Robert Marcus

47. Prevention of Osteoporosis

256

(6)

Robert Lindsay

48. Nutrition and Osteoporosis

262

(2)

Robert P. Heaney

49. Evaluation and Treatment of Postmenopausal Osteoporosis

264

(8)

Michael Kleerekoper

Louis V. Avioli

50. The Special Problem of Hip Fracture

272

(3)

Eric S. Orwoll

51. Juvenile Osteoporosis

275

(3)

Michael E. Norman

52. Glucocorticoid and Drug-Induced Osteoporosis

278

(5)

Barbara P. Lukert

53. Osteoporosis in Men

283

(3)

Jeffrey A. Jackson

54. Hyperthryoidism, Thyroid Hormone Replacement, and Osteoporosis

286

(3)

Daniel T. Baran

55. Miscellaneous Causes of Osteoporosis

289

(4)

Socrates E. Papapoulos

56. Orthopeidc Complications of Osteoporosis

293

(6)

Thomas A. Einhorn

57. Osteoporosis and Rheumatic Diseases

299

(2)

Steven R. Goldring

58. Nutritional Rickets and Osteomalacia

301

(5)

Gordon L. Klein

59. Metabolic Bone Disease in Gastrointestinal, Hepatobiliary, and Pancreatic Disorders

306

(5)

D. Sudhaker Rao

Mahalakshmi Honasoge

60. Vitamin D-Dependent Rickets

311

(5)

Uri A. Liberman

Stephen J. Marx

61. Hypophosphatemic Vitamin D-Resistant Rickets

316

(3)

Francis H. Glorieux

62. Tumor-Induced Rickets and Osteomalacia

319

(7)

Marc K. Drezner

63. Hypophosphatasia

326

(2)

Michael P. Whyte

64. Fanconi Syndrome and Renal Tubular Acidosis

328

(5)

Russell W. Chesney

65. Drug-Induced Osteomalacia

333

(4)

Daniel D. Bikle

66. Metabolic Bone Disease of Total Parenteral Nutrition

337

(4)

Gordon L. Klein

67. Renal Osteodystrophy in Adults and Children

341

(21)

William G. Goodman

Jack W. Coburn

Eduardo Slatopolsky

Isidro B. Salusky

Section VI. Genetic, Developmental, and Dysplastic Skeletal Disorders

362

(28)

Section VI. Introduction

362

(1)

Michael P. Whyte

68. Sclerosing Bone Dysplasias

363

(17)

Michael P. Whyte

69. Fibrous Dysplasia

380

(2)

Michael P. Whyte

70. Osteogenesis Imperfecta

382

(3)

Michael P. Whyte

71. Chondrodystrophies and Mucopolysaccharidoses

385

(5)

Michael P. Whyte

Section VII. Acquired Disorders of Cartilage and Bone

390

(19)

Section VII. Introduction

390

(1)

Michael P. Whyte

72. Skeletal Neoplasms

391

(8)

Michael P. Whyte

73. Ischemic Bone Disease

399

(4)

Michael P. Whyte

74. Infiltrative Disorders of Bone

403

(6)

Michael P. Whyte

Section VIII. Paget's Disease

409

(13)

75. Paget's Disease of Bone

409

(13)

Ethel S. Siris

Section IX. Extraskeletal (Ectopic) Calcification and Ossification

422

(10)

Section IX. Introduction

422

(2)

Michael P. Whyte

76. Tumoral Calcinosis

424

(2)

Michael P. Whyte

77. Dermatomyositis

426

(2)

Michael P. Whyte

78. Fibrodysplasia (Myositis) Ossificans Progressive

428

(4)

Michael P. Whyte

Frederick S. Kaplan

Eileen Shore

Section X. Nephrolithiasis

432

(15)

Section X. Introduction

432

(1)

Murray J. Favus

79. Nephrolithiasis

433

(5)

Fredric L. Coe

Joan H. Parks

80. Urologic Aspects of Nephrolithiasis Management

438

(9)

James E. Lingeman

Section XI. Appendix

447

(20)

i. Growth Charts for Males and Females

447

(2)

ii. Ossification Centers

449

(2)

iii. Laboratory Values of Importance for Calcium Metabolism and Metabolic Bone Disease

451

(2)

iv. Mineral and Vitamin D RDAs for Infants, Children, and Adults

453

(1)

v. Formulary of Drugs Commonly Used in Treatment of Mineral Disorders

454

(4)

vi. Structure of Naturally Occurring Vitamin D and Synthetic Analogs

458

(1)

vii. Dynamic Tests

459

(4)

viii. Bone Density Reference Data

463

(4)

Subject Index

467

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