Asymmetric Synthesis With Chemical and Biological Methods

Edited by two of the leading researchers in the field, this book provides a deep, interdisciplinary insight into stoichiometric and catalytic reactions in this continuously expanding area. A plethora of top German scientists with an international reputation covers various aspects, from classical organic chemistry to process development, and from the theoretical background to biological methods using enzymes. Throughout the focus is on the development of new synthetic methods in asymmetric synthesis, the synthesis of natural and bioactive compounds and the latest developments in both chemical and biological methods of catalysis, as well as the investigation of special technical and biotechnical aspects.

Dieter Enders completed his PhD at the Justus-Liebig-Universit+ñt Giessen under the supervision of D. Seebach. After postdoctoral studies at Harvard University with E. J. Corey, he returned to Giessen and completed his habilitation. He became associate professor at the Universit+ñt Bonn in 1980, and moved to his present position as Professor of Organic Chemistry at the RWTH Aachen in 1985. He has received many awards (Leibniz-Award of the DFG, Emil Fischer Award of the GDCh, Yamada Award, Japan) for his research, which focuses on the asymmetric synthesis of biologically active compounds and the development of new synthetic methods.

Karl-Erich Jaeger was born in Dortmund and studied biology and chemistry at the Ruhr-University Bochum, where he received his PhD. After postdoctoral studies with Robert E.W. Hancock at the Department of Microbiology of the University of British Columbia, he received his habilitation in Bochum in 1995. Karl-Erich Jaeger is currently Professor at the Heinrich-Heine University of D++sseldorf and Director of the Institute of Molecular Enzyme Technology at the Research Centre J++lich. His research interests are enantionselective biocatalyis and directed evolution of enzymes.