Estrogens, Progestins, and Their Antagonists

Text on the current views, uses, and issues of estrogens and progestins, for molecular and cell biologists, pharmacologists, and endocrinologists. Considers benefits/risks of replacement therapy. DNLM: Estrogen Replacement Therapy.

Foreword

xi

V.K. Moudgil

Introduction to Volume 1

xiii

Edward J. Pavlik

Contributors

xix

Part I: New Applications and Concepts Involving Estrogens and Progestins

Benefits and Risks of Hormone Replacement Therapy

3

(48)

Raymond Klein

Laini Berlin

Phytoestrogen Effects in Humans Relative to Risk for Cardiovascular Disease, Breast Cancer, Osteoporosis, and Menopausal Symptoms

51

(22)

James W. Anderson

Dietary Indoles with Antiestrogenic Activity in Common Vegetables and Their Implications

73

(26)

Stephen H. Safe

Ichen Chen

Weston Porter

Treatment for Infertility and Risk of Female Cancers

99

(16)

Mary Anne Rossing

Antiestrogen Resistance in Human Breast Cancer

115

(46)

Edward J. Pavlik

Katherine Nelson

Suseela Srinivasan

Paul D. DePriest

Daniel E. Kenady

Evolving Therapies for Prostatic Carcinoma, Encompassing Orchiectomy, Estrogens, and Estramustine

161

(16)

David P. Wood Jr.

Regulatory Aspects of Estrogens and Progestins in Human Food: Past, Present, and Future

177

(20)

John K. Leighton

Margaret A. Miller

Part II: Novel Hormonal Ligands

Estrogen and Progestin Radiopharmaceuticals for Imaging Breast Cancer

197

(46)

John A. Katzenellenbogen

The Utility of Fluorescent Estrogens for Receptor Imaging

243

(30)

Richard J. Miksicek

Comparative Review of Recently Introduced Oral Contraceptives Containing Norgestimate, Desogestrel and Gestodene and Older Oral Contraceptives

273

(24)

Thomas H. Schwend

Joel S. Lippman

Antiprogestins: Past, Present, and Future

297

(24)

Horst Michna

Yukishige Nishino

Karsten Parczy

Martin R. Schneider

Keyword Index

321

Foreword

xi

V.K. Moudgil

Introduction to Volume 2

xiii

Edward J. Pavlik

About Volume 1

xvi

Edward J. Pavlik

Contributors

xix

Part I: Estrogen and Progestin Physiological Function

Pituitary and Brain Actions of Estrogen and Progesterone in the Regulation of Primate Prolaction Secretion

3

(44)

C. L. Bethea

S. G. Kohama

M. Pecins-Thompson

Saccharomyces cerevisiae As a Model System to Study Steroid Hormone Receptors

47

(22)

Brandee L. Wagner

Donald P. McDonnell

Physiological Findings from Transgenic Mouse Models with Altered Levels of Estrogen Receptor Expression

69

(32)

John F. Couse

Vicki L. Davis

Kenneth S. Korach

Part II: Molecular Biology of Steroid Receptors and Gene Expression

New Models and Insights in Steroid Hormone Action

101

(22)

Lisa L. Wei

A Role for Progesterone in Multidrug Resistance

123

(30)

Shyamali Mallick

Susan Band Horwitz

Dominant Negative Activity by Estrogen and Progesterone Receptors

153

(16)

Paul M. Yen

Estrogen and Progesterone Receptors in Human Endometrial Cancer

169

(22)

Kian Behbakht

Jeff Boyd

Part III: Factors Enhancing Receptor Function

Facilitated Binding of Steroid Hormone Receptors to Target DNA by the Chromatin High-Mobility Group Protein-1: Protein Manipulation of DNA Structure

191

(26)

Dean P. Edwards

Paul Prendergast

Use of FK506 and Its Analogs in Studying Progesterone Signaling

217

(14)

Ping-Kaung Ku Tai

Lee E. Faber

Keyword Index

231

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Estrogens, Progestins, and Their Antagonists

Summary

Table of Contents

Supplemental Materials

FREE SHIPPING

Rent More, Save More! Use code: BBRENTAL

5% off 1 book, 7% off 2 books, 10% off 3+ books

Estrogens, Progestins, and Their Antagonists

Summary

Table of Contents

Supplemental Materials

Digital License