Single-Molecule Studies of Nucleic Acids and Their Proteins

David Bensimon, Research Director and Professor, LPS-ENS, PSL, CNRS and Department of Chemistry and Biochemistry, UCLA, USA, Vincent Croquette, Research Director, LPS-ENS, PSL, CNRS, France,Jean-Francois Allemand, Professor, LPS-ENS, PSL, CNRS, France,Xavier Michalet, Researcher, Department of Chemistry and Biochemistry, UCLA, USA,Terence Strick, Research Director and Principle Investigator, IBENS, PSL, CNRS, France

David Bensimon and Vincent Croquette have been co-leaders of a group at the LPS-ENS that has been studying single DNA molecules and their interactions with proteins since 1991. Jean-Francois Allemand, Terence Strick and Xavier Michalet have been their students and collaborators ever since. They have jointly developed magnetic traps and have been studying various aspects of single molecule DNA/protein transactions. Since joining the lab of Professor S. Weiss at UCLA , Xavier Michalet has been focusing on the use of fluorescent and spectroscopic methods to study single biomolecules.