Sleep and Mental Illness

The diagnosis of mental illness is frequently accompanied by sleep problems; conversely, people experiencing sleep problems may subsequently develop mental illness. Sleep and Mental Illness looks at this close correlation and considers the implications of research findings that have emerged in the last few years. Additionally, it surveys the essential concepts and practical tools required to deal with sleep and co-morbid psychiatric problems. The volume is divided into three main sections: basic science, neuroendocrinology, and clinical science. Included are over 30 chapters on topics such as neuropharmacology, insomnia, depression, dementia, autism, and schizophrenia. Relevant questionnaires for the assessment of sleep disorders, including quality-of-life measurement tools, are provided. There is also a summary table of drugs for treating sleep disorders. This interdisciplinary text will be of interest to clinicians working in psychiatry, behavioral sleep medicine, neurology, pulmonary and critical care medicine.

S. R. Pandi-Perumal is President and Chief Executive Officer, Somnogen Inc, New York, USA. Milton Kramer is Professor of Clinical Psychiatry, University of Illinois at Chicago, USA.

List of contributors	p. ix
Foreword: Sleep as a model for mental illness	p. xiv
Preface	p. xvii
Acknowledgments	p. xix
Basic science
Neuropharmacology of mental illness	p. 1
Effects of antidepressants on gene expression	p. 7
Genetics of circadian rhythms in relation to mental illness	p. 22
Neurochemistry and neurophysiology of sleep abnormalities associated with depression	p. 29
Neurobiology of insomnia	p. 51
Animal models of sleep and stress: implications for mental illness	p. 60
Insomnia and brain orexin alterations in depressive illness	p. 68
Neuroendocrinology
Pathophysiology of changes in sleep EEG and hormone secretion	p. 83
Eating and sleep disorders: shared mechanisms?	p. 95
Sleep-endocrine relationships in depressed women across the reproductive cycle	p. 101
Melatonin and mental illness	p. 119
Dim light melatonin onset in psychiatric disorders	p. 130
Clinical science
Classification of sleep disorders	p. 139
Insomnia: a risk for future psychiatric illness	p. 154
The association between sleep disorders and depression: implications for treatment	p. 165
Sleep in late-life depression	p. 173
Long-term effects of antidepressants on sleep	p. 183
Antidepressant-induced alteration of sleep EEG	p. 202
Rapid eye movement sleep interruption as a therapy for major depression	p. 222
Sleep in dementia	p. 226
Sleep and attention-deficit/hyperactivity disorder: science and clinical practice	p. 242
Interaction between primary sleep disorders and attention-deficit/hyperactivity disorder	p. 252
Sleep in autism spectrum disorders	p. 261
Sleep in schizophrenia	p. 265
Fatigue and sleepiness in affective illness	p. 270
Sleep in seasonal affective disorder	p. 283
Sleep during antipsychotic treatment	p. 289
Sleep-related memory consolidation in mental illnesses	p. 295
Sleep-associated cognitive side effects of psychoactive medications	p. 309
Sleep and post-traumatic stress disorder	p. 326
Sleep and substance use and abuse	p. 341
Sleep following traumatic brain injury	p. 353
Sleep in borderline personality disorder	p. 368
Dream differences in psychiatric patients	p. 375
Forensic issues of sleep in psychiatric patients	p. 383
Sleep abnormalities and Prader-Willi syndrome	p. 405
Index	p. 416
Table of Contents provided by Ingram. All Rights Reserved.

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Sleep and Mental Illness

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Author Biography

Table of Contents

Supplemental Materials