Statistics in Toxicology A Volume in Memory

This collection of papers on aspects of statistics in toxicology is will be of interest to all medical statisticians. It offers findings from numerous leading experts from around the world including A. Whitehead and R. N. Connor (University of Reading), L. Ryan (Harvard), A. P. Grieve (Pfizer Research), K.J. Risko (Northern Telecom), and B.H. Margolin (University of North Carolina). This is the latest in the popular Royal Statistical Society Lecture Series, and will be essential reading for all those involved in this area.

David Williams
Review Papers
Are animal experiments in toxicological research the 'right' size?
Estimating dose-response for toxic end-points
A literature review of statistical methods for the analysis of general toxicology datas
Statistical analysis of genetic toxicology test data
Overdispersion
Some observations on detecting extra-binomial variability within the beta-binomial model
C(alpha) tests for homogeneity of proportions in toxicology in the presence of beta-binomial overdispersion
Overdispersion in logistic-linear models
LD50 Estimation
On likelihood and Bayesian methods for interval estimation of the LD50
The analysis of grouped longitudinal mortality data allowing for variable natural mortality
Statistical evaluation of the fixed-dose procedure
General Applications
Statistical analysis of overdispersed multinomial data from development toxicity studies
Trend tests for clustered data, Myrto Lefkopoulou
Exploratory and model-based inference in toxicokinetics
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Statistics in Toxicology A Volume in Memory of David A. Williams

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