Stem Cells From Biology to Therapy, 2 Volumes

This third in the Current Topics in Molecular Cell Biology and Molecular Medicine Series contains a careful selection of new and updated, high-quality articles from the well-known Meyer's Encyclopedia, describing new perspectives in stem cell research. The 26 chapters are divided into four sections: Basic Biology, Stem Cells and Disease, Stem Cell Therapy Approaches, and Laboratory Methods, with the authors chosen from among the leaders in their respective fields.

This volume represents an essential guide for students and researchers seeking an overview of the field.

Preface ix

Volume 1

Part I Basic Biology 1

1 Epigenetic Regulation in Pluripotent Stem Cells 3
Lin Liu and Lingyi Chen

2 Induced Pluripotent Stem Cells 41
Kazutoshi Takahashi and Shinya Yamanaka

3 Naturally Occurring Adult Pluripotent Stem Cells 63
Henry E. Young and Asa C. Black Jr

4 Spermatogonial stem cell (SSCs) system 95
G. Ian Gallicano and Shenglin Chen

5 Stem Cell Dormancy: Maintaining a Reserved Population 119
John M. Perry, Xi C. He, Ryohichi Sugimura and Linheng Li

6 Stem Cells in the Adult Brain: Neurogenesis 133
Michael A. Bonaguidi, Guo-li Ming, and Hongjun Song

7 Embryonic Stem Cells 151
Mahendra Rao

Part II Laboratory Methods 175

8 Cardiomyocytes from Human Embryonic Stem Cells 177
Xiu Qin Xu, Manasi Nandihalli, Kar Tong Tan, and William Sun

9 Cloned Mice from Adult Stem Cells 209
Haruko Obokata and Teruhiko Wakayama

10 Cloned Mice from Embryonic Stem Cells 233
Chong Li and Teruhiko Wakayama

11 Haploid Embryonic Stem Cells 255
Ni Hong and Yunhan Hong

12 Muscle Stem Cells: Their Discovery, Properties, and In-Vitro Manipulation 273
Sean McFarland, Ioanna Pagani, and Irina Conboy

13 Nuclear Transfer for Cloning Animals 299
Andras Dinnyes, Xiuchun Cindy Tian, and Bj¨orn Oback

14 Induction of Pluripotent Stem Cells from Umbilical Cord Blood 345
Kejin Hu and Igor Slukvin

15 Development and Renewal of Ventricular Heart Muscle from Intrinsic Progenitor Cells 371
William C.W. Chen and Bruno P´eault

Volume 2

Part III Stem Cell Therapy 389

16 Gene Therapy of Genetic Diseases of Blood Cells 391
Gabriela Kuftinec, Jennifer Wherley and Donald B. Kohn

17 Mesenchymal Stem Cells Characteristics, Niches, and Applications for Cell Therapy 429
Joni H. Yl¨ostalo and Thomas J. Bartosh

18 Stem Cells and Parkinson’s Disease 471
Emma Lane, Maria Sundberg, and Jan Pruszak

19 Stem Cell-Based Approaches to Spinal Cord Injury 503
Alexa L. Reeves and Hans Keirstead

20 Therapeutics against Cancer Stem Cells: Targeting the Root of Cancer 521
Kristen M. Smith and Catriona H. M. Jamieson

21 Translating Stem Cells to the Clinic: From Modeling Disease to Cellular Products 573
Emmanuel Nivet, Ignacio Sancho-Martinez, and Juan Carlos Izpisua Belmonte

Part IV Stem Cells and Disease 601

22 Cancer Stem Cells 603
Mei Zhang and Jeffrey M. Rosen

23 Normal and Neoplastic Stem Cells 627
Axel Schulenburg and Brigitte Marian

24 Prostate Tissue Stem Cells and Prostate Cancer Progression 655
Collene R. Jeter and Dean G. Tang

25 The Stem Cell Niche and Its Role in Self-Renewal, Aging, and Malignancy 677
Peter Breslin S.J., Andrew Volk and Jiwang Zhang

26 Stem Cells and Colon Cancer 727
Simone Di Franco, Antonina Benfante, Flora Iovino, Sebastiano Bonventre, Francesco Dieli, Giorgio Stassi and Matilde Todaro

Index 751

The New copy of this book will include any supplemental materials advertised. Please check the title of the book to determine if it should include any access cards, study guides, lab manuals, CDs, etc.

The Used, Rental and eBook copies of this book are not guaranteed to include any supplemental materials. Typically, only the book itself is included. This is true even if the title states it includes any access cards, study guides, lab manuals, CDs, etc.