Targeted Delivery of Small and Macromolecular Drugs

Site-specific drug delivery and targeting is attracting much research interest from both academia and industry, but because of the many challenges faced in the development of these systems, only a handful of targeted therapies have successfully made it into clinical practice. Bringing together leading field experts, Targeted Delivery of Small and Macromolecular Drugs summarizes current progress with a focus on the novel ideas being explored to overcome these challenges.Focuses on the Targeted Drug Delivery Technologies that Utilize both Systemic and Local Routes of Administration Leading experts discuss some of the most promising strategies for drug targeting. They also cover targeted drug delivery platforms and technologies at various stages of clinical and preclinical development, including:'¢ Active targeting '¢ Nucleic acid delivery and targeting '¢ Intracellular/Organelle-Specific Strategies '¢ Prodrug Strategies '¢ Organ or Tissue-Specific drug delivery '¢ Drug-Polymer Conjugates and Micelles '¢ Stimuli-Responsive systemsTargeted Delivery of Small and Macromolecular Drugs demonstrates why targeted delivery is one of the most exciting contributions pharmaceutical sciences can make to drug therapy.