Theory and Applications of Heat Transfer in Humans, 2 Volume Set

An authoritative guide to theory and applications of heat transfer in humans 

Theory and Applications of Heat Transfer in Humans 2V Set offers a reference to the field of heating and cooling of tissue, and associated damage. The author—a noted expert in the field—presents, in this book, the fundamental physics and physiology related to the field, along with some of the recent applications, all in one place, in such a way as to enable and enrich both beginner and advanced readers.  The book provides a basic framework that can be used to obtain ‘decent’ estimates of tissue temperatures for various applications involving tissue heating and/or cooling, and also presents ways to further develop more complex methods, if needed, to obtain more accurate results.  The book is arranged in three sections: The first section, named ‘Physics’, presents fundamental mathematical frameworks that can be used as is or combined together forming more complex tools to determine tissue temperatures; the second section, named ‘Physiology’, presents ideas and data that provide the basis for the physiological assumptions needed to develop successful mathematical tools; and finally, the third section, named ‘Applications’, presents examples of how the marriage of the first two sections are used to solve problems of today and tomorrow.

This important text is the vital resource that:

• Offers a reference book in the field of heating and cooling of tissue, and associated damage.
• Provides a comprehensive theoretical and experimental basis with biomedical applications
• Shows how to develop and implement both, simple and complex mathematical models to predict tissue temperatures
• Includes simple examples and results so readers can use those results directly or adapt them for their applications

Designed for students, engineers, and other professionals, a comprehensive text to the field of heating and cooling of tissue that includes proven theories with applications. The author reveals how to develop simple and complex mathematical models, to predict tissue heating and/or cooling, and associated damage. 

EDITED BY

DEVASHISH SHRIVASTAVA, PHD, works for US FDA, served as chair of the ISMRM MR safety study group committee and represented the US in standardization committees dealing with safety in MRI. His background and research interest are in developing validated bioheat transfer models to predict in vivo tissue heating in humans due to the use of medical devices and during occupational and recreational activities.

List of Contributors to Volume 1 xxv

Preface xxvii

Supplementary Material xxxi

VOLUME I

Section I Theory: Physics 1

1 A Generic Thermal Model for Perfused Tissues 3
Devashish Shrivastava

2 Alternate Thermal Models to Predict in vivo Temperatures 15
Devashish Shrivastava

3 Thermal Effects of Blood Vessels 25
Devashish Shrivastava

4 Generating Blood Vasculature for Bioheat Computations 33
David Porter

5 Whole-Body Human Computational Models and the Effect of Clothing 53
Daniela Zavec Pavlinic and Eugene H.Wissler

6 Models of the Cardiovascular System 71
M. Keith Sharp

7 Lumped ParameterModeling of Human Respiratory System 119
Rachana Visaria

8 Inverse Heat Transfer for Biomedical Applications 133
Elaine P. Scott

9 Fundamentals of Propagation of Light in Tissue 153
Do-Hyun Kim

10 Ultrasound Propagation in Tissue 167
Joshua E. Soneson

11 ElectromagneticWaves and Fields in the Human Body in MRI 183
Jinfeng Tian

12 Electromagnetic Distribution in Tissue with Conductive Devices 203
John Nyenhuis

13 Techniques for Fast Computation 233
David Porter

14 Principles of TemperatureMeasurement with Temperature Probes in Bioheat Transfer Applications 261
Pradyumna Ghosh

15 Non-Invasive Thermometry with Magnetic Resonance Imaging 267
Henrik Odéen and Dennis L. Parker

16 Ultrasound Thermography: Principles, Methods, and Experimental Results 301
Emad S. Ebbini

17 Thermal Property Measurements 333
Jonathan W. Valvano

18 Measurement and Thermal Dependence of Biological Tissue Optical Properties 355
William C. Vogt, Jennifer K. Barton, Anant Agrawal and T. Joshua Pfefer

19 Measurement of Dielectric Properties of Tissue 379
Anand Gopinath

20 Micro- and Nanoscale Calorimetry for Biomedical Applications 393
Harishankar Natesan and John C. Bischof

VOLUME II

Section II Theory: Physiology 433

21 Cardiovascular and Metabolic Responses to Thermal Insults 435
Thad E.Wilson

22 Morphological and Physiological Considerations for the Modelling of Human Heat Loss 463
Nigel A.S. Taylor and Sean R. Notley

23 Adjustments in Thermoregulation during Radiofrequency Heating 501
Christopher J. Gordon

24 Burn: A Clinical Perspective 513
Mayank Singh and Surya Prakash

25 Response of the Thermoregulatory Systemto Toxic Chemicals 529
Christopher J. Gordon

26 Irreversible Tissue Thermal Alterations: Skin Burns, Thermal Damage and Cell Death 553
John Pearce

27 Models andMechanisms of Tissue Injury in Cryosurgery 591
Anthony T. Robilotto, John M. Baust, Robert G. Van Buskirk and John G. Baust

Section III Applications 619

28 In vivo Radiofrequency Heating in a 3T MRI Scanner 621
Jinfeng Tian and Devashish Shrivastava

29 Magnetic Nanoparticle Hyperthermia in Cancer Treatment: History, Mechanism, Imaging-Assisted Protocol Design, and Challenges 631
Alexander LeBrun and Liang Zhu

30 Modeling Combined Cryosurgery and Hyperthermia with Thermally Significant Blood Vessels 669
Gang Zhao, Fazil Panhwar and Zhongrong Chen

31 Cryoablation for the Treatment of Solid Cancers and Pain Management 687
Satish Ramadhyani

32 Effect of Blood Flow on MRI-Induced Heating near Stents 715
Devashish Shrivastava

33 Skin Burns 723
John P. Abraham, Brian D. Plourde, Lauren J. Vallez, Brittany B. Nelson-Cheeseman, John R. Stark, Ephraim M. Sparrow and JohnM. Gorman

34 Surface and Endovascular Cooling: Methods, Models, and Measurements 741
Thomas L. Merrill and Jennifer E.Mitchell

35 Estimation ofWind Chill Equivalent Temperatures (WCETs) 753
Avraham Shitzer

36 Temperature Postmortem: Theories, Models, and Measurements 773
Michael Hubig, Holger Muggenthaler, Senta Niederegger and Gita Mall

Index 809

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