Tissue Engineering and Novel Delivery Systems

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ISBN: 9780824747862 | 0824747860
Cover: Hardcover
Copyright: 11/4/2003

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Essential to anyone working in the field, this reference focuses on rencent advancements in tissue construction, repair and regeneration-examining developments in gene and drug therapy, the evolution of tissue-engineered products, and new technologies for the design of functional tissues and organ systems.

Preface

iii

PART I: BIOCOMPATIBILITY AND THE BIOMATERIAL-TISSUE INTERFACE

1. Role of Extracellular Matrix Remodeling in Advanced Biocompatibility

(30)

M. Cannas, M. Bosetti, M. Sabbatins, and F. Renò

2. Elastic Protein-Based Biomaterials: Elements of Basic Science, Controlled Release, and Biocompatibility

(24)

Dan W. Urry, T. Copper Woods, Larry C. Hayes, Jie Xu, David T. McPherson, Masamichi Iwama, Masakazu Furutan, Toshio Hayashi, Mitsuhiro Murata, and Timothy M. Parker

3. Noninvasive Measurement of the Transient Adhesion of Cells to Blood Contacting Surfaces

(20)

Jun Li, M. Kurt Sly, Robert Chao, Anca Constantinescu, Padmakar Kulkarni, Michael Fessen, and Robert Eberhart

4. Clinical Properties and Healing Characteristics of e-PTFE Vascular Grafts and Their Effects on Long-Term Patency

(32)

Glenn C. Hunter, Hana Holubec, Alex Westerband, David A. Bull, Kenneth J. Woodside, and Charles W. Putnam

5. Biomaterials and Stent Technology

107

(24)

Kytai T. Nguyen, Shih-Horng Su, Meital Zilberman, Pedram Bohluli, Peter Frenkel, Richard Timmons, Lipine Tang, and Robert Eberhart

6. Long-Term Evaluation of a Novel Tissue Adhesive (BioGlue) for Use in Surgery

131

(10)

Nancy Perlman, Charles W. Hewitt, Steve D. Lenz, K Umit Yuksel, Steven W. Marra, Jean-Luc V. Tran, Jonathan H. Cilley, Vincent A. Simonetti, and Anthony J. DelRossi

PART II: TISSUE ENGINEERING EQUIVALENTS

7. Bioengineered Skin Reconstituted from Cultured Epidermis and Cryopreserved Dermis: Converting Cryopreserved Skin Allografts into a Permanent Skin Substitute

141

(14)

Hanna Ben-Bassot

8. Cutaneous Gene Therapy with Cultured Skin Substitutes

155

(18)

Dorothy M. Supp and Steven T. Boyce

9. Surface Properties of Polymeric Biomaterials and Their Modification for Tissue Engineering Applications

173

(24)

Ayscen Tezcaner and Vasif Hasirci

10. Principles of Living Organ Reconstruction by Tissue Engineering

197

(32)

Lucie Germain, François Berthod, Véronique Moulin, Francine Goulet, and François A. Auger

11. Recombinant Protein Scaffolds for Tissue Engineering

229

(24)

Jerome A. Werkmeister, Paul R. Vaughan, Yong Peng, and John A.M. Ramshaw

12. Auricular Cartilage Tissue Engineering

253

(12)

Doreen Rosenstrauch, Kamuran Kadipasaoglu, Harnath Shelat, Pierre Zoldhelyi, and O.H. Frazier

13. Rheology of Biological Fluids and Their Substitutes

265

(16)

Assunta Borzacchiello, Luigi Ambrosio, Paolo Netti, and Luigi Nicolais

PART III: DELIVERY SYSTEMS

14. Production of Microbial Polyesters and Their Application in the Construction of Biodegradable, Controlled Antibiotic Release Systems

281

(24)

Vasif Hasirci, F. Korkusuz, N. Akkas, E. Bayramli, N. Hasirci, F. Severcan, M. Timucin, and G. Alaeddinoglu

15. Microencapsulation of Protein Drugs: A Novel Approach

305

(28)

Yoon Yeo and Kinam Park

16. Polymeric Gene Delivery Systems

333

(36)

Goldie Kaul and Monsoon Amiji

17. Bioactive Molecules and Biodelivery Systems

369

(24)

Filiz Oner and H. Siiheylä Kas

18. Biodegradable Nanoparticles as Drug Delivery Systems for Parenteral Administration

393

(30)

Michael Chorny, Hagit Cohen-Sacks, Ilia Fishbein, Haim D. Danenberg, and Gershon Golomb

19. Biodegradable Hydrogels as Drug Controlled Release Vehicles

423

(40)

C.C. Chu

20. Growth Factor Delivery by a Cloned Multipotent Cell from Bone Marrow Stroma Potentiates Bone Repair

463

(12)

Nigel M. Azer, Quanjun Cui, Ing-Lin Chang, T. Lisle Whitman, Chang Hahn, Gwo-Jaw Wang, and Gary Balian

21. New Synthetic Biodegradable Polymers for Bone Morphogenetic Protein Delivery Systems

475

(8)

Naoio Saito, Hiroshi Horiuchi, Narumichi Murakami, Jun Takahashi, Takao Okada, Kazutoshi Nozaki, and Kunio Takaoka

22. Nanosized Biosensors and Delivery Vehicles

483

(22)

Agnes E. Ostafin, Hiroshi Mizukami, and Joel P. Burgess

PART IV: EMERGING CONCEPTS IN BIOMATERIALS

23. Relationships Between Biomaterials and Biosensors

505

(16)

Kirk J. Bundy

24. Collagen: The Next Generation of Resorbable Biodevices in Surgery

521

(22)

Frank DeLustro, Louis Seht, Trudy Estridge, and Donald Wallace

25. Polyhydroxybutyrate and Its Copolymers: Applications in the Medical Field

543

(20)

Fatma Kok and Vasif Hasirci

26. From Polymer Chemistry and Physicochemistry to Nanoparticulate Drug Carrier Design and Applications

563

(36)

C. Vauthier, E. Fattal, and D. Labarre

27. Hyperspectral Analysis of Collagen Infused with BisGMA-Based Polymeric Adhesive

599

(34)

Paulette Spencer, J. Lawrence Katz, Massood Tabib-Azar, Yong Wang, Ajay Wagh, and Tsutomu Nomura

Index

633

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Tissue Engineering and Novel Delivery Systems

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Table of Contents

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