USMLE Road Map Pharmacology, Second Edition

You'll never find an easier, more efficient, and more focused way to ace the pharmacology and pharmacology-related questions on the Usmle and course examinations than the Usmle Road Map. Designed to provide maximum learning in minimum time, this Usmle Road Map offers a concise, creative, and well-illustrated new approach to mastering pharmacology.

Using the Road Map Series for Successful Review

vii

Acknowledgments

ix

General Principles of Pharmacology

1

(13)

Definitions

1

(1)

Pharmacokinetic Principles

1

(5)

Pharmacodynamic Principles

6

(5)

Drug Development and Regulation

11

(3)

Clinical Problems

11

(2)

Answers

13

(1)

Autonomic Nervous System Pharmacology

14

(17)

Autonomic Anatomy

14

(1)

Transmitter Biochemistry

14

(3)

Physiology of Autonomic Action

17

(3)

Cholinomimetic Drugs

20

(2)

Cholinolytic Drugs and Pralidoxime

22

(2)

Sympathomimetics

24

(3)

Adrenoceptor Blockers

27

(4)

Clinical Problems

29

(1)

Answers

30

(1)

Drug Therapy for Cardiovascular Diseases

31

(18)

Hypertension

31

(5)

Angina Pectoris

36

(2)

Heart Failure

38

(3)

Cardiac Arrhythmias

41

(3)

Diuretics and Other Drugs Acting on the Kidney

44

(5)

Clinical Problems

47

(1)

Answers

48

(1)

Drugs for Allergy, Inflammation, and Blood and Immune Disorders

49

(15)

Histamine and Antihistaminics

49

(1)

Serotonin and Related Drugs

49

(3)

Eicosanoids

52

(1)

Nonsteroidal Anti-inflammatory Drugs and Drugs Used in Fever and Minor Pain and Headache

53

(1)

Drugs Used in Gout

54

(1)

Antilipid Drugs

55

(1)

Anticoagulants, Antiplatelet Drugs, and Fibrinolytics

56

(1)

Drugs Used in Anemias and Other Disorders of Blood Formation

57

(2)

Drugs Used in Asthma

59

(5)

Clinical Problems

61

(1)

Answers

62

(2)

Central Nervous System Drugs

64

(25)

Introduction to the Central Nervous System (CNS) Drugs

64

(1)

Sedative-Hypnotics

64

(4)

Antiepileptic Drugs (AEDs)

68

(3)

General Anesthetics

71

(1)

Local Anesthetics

72

(1)

Skeletal Muscle Relaxants

73

(2)

Drugs for Parkinsonism and Other Movement Disorders

75

(2)

Drugs for Psychoses and Bipolar Disorder

77

(2)

Antidepressants

79

(2)

Opioid Analgesics

81

(3)

Drugs of Abuse

84

(5)

Clinical Problems

85

(2)

Answers

87

(2)

Hormones and Other Endocrine Agents

89

(13)

Hypothalamic and Pituitary Drugs

89

(1)

Thyroid Drugs

90

(1)

Adrenal Steroids and Antagonists

91

(2)

Gonadal Drugs, Antagonists, and Inhibitors

93

(1)

Pancreatic Drugs

94

(4)

Drugs That Affect Bone Mineral Metabolism

98

(4)

Clinical Problems

99

(2)

Answers

101

(1)

Antimicrobial Agents: Antibiotics

102

(17)

Inhibitors of Cell Wall Synthesis: Penicillins

102

(2)

Inhibitors of Cell Wall Synthesis: Cephalosporins, Carbapenems, and Vancomycin

104

(2)

Inhibitors of Protein Synthesis: Macrolides, Clindamycin, Tetracyclines, and Chloramphenicol

106

(2)

Inhibitors of Protein Synthesis: Aminoglycosides, Streptogramins, and Linezolid

108

(2)

Inhibitors of Folic Acid Synthesis: Sulfonamides and Trimethoprim

110

(2)

Inhibitors of Nucleic Acid Synthesis: Fluoroquinolones

112

(1)

Antimycobacterial Drugs

113

(1)

Miscellaneous Antimicrobials

114

(5)

Clinical Problems

115

(2)

Answers

117

(2)

Antifungal, Antiviral, and Antiparasitic Drugs

119

(13)

Antifungal Drugs

119

(2)

Antiviral Drugs

121

(4)

Antiparasitic Drugs

125

(7)

Clinical Problems

127

(4)

Answers

131

(1)

Anticancer Drugs and Immunopharmacology

132

(12)

Cancer Chemotherapy

132

(4)

Immunopharmacology

136

(8)

Clinical Problems

139

(3)

Answers

142

(2)

Toxicology

144

(9)

Introduction

144

(1)

Environmental Chemicals

144

(1)

Agricultural Chemicals

145

(1)

Heavy Metals

146

(1)

Management of Poisoning

146

(7)

Clinical Problems

149

(2)

Answers

151

(2)

Special Topics

153

(12)

Gastrointestinal Pharmacology

153

(2)

Vaccines and Other Immunization Materials

155

(1)

Botanicals and Nutritional Supplements

156

(3)

Drug Interactions

159

(6)

Clinical Problems

160

(3)

Answers

163

(2)

Appendix

165

(8)

Index

173

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USMLE Road Map Pharmacology, Second Edition

Summary

Table of Contents

Supplemental Materials