- ISBN: 9780879696849 | 0879696842
- Cover: Hardcover
- Copyright: 6/26/2007
This extensively illustrated, full-color textbook offers an introductory discussion on the history of experiments and ideas in the development of molecular biology and provides an account of the ideas underpinning evolutionary theory. It covers the origins and diversity of life, evolutionary processes, human evolution, and methods and tools.
David B. Goldstein is Director of the Center for Population Genomics and Pharmacogenetics at the Duke University Medical Center.
| About the Authors | p. x |
| Preface | p. xi |
| Aim and Scope of the Book | p. 1 |
| Evolutionary Biology Describes the History of Life and Explains Why Organisms Are the Way They Are | p. 1 |
| Evolutionary Biology Is a Valuable Tool | p. 3 |
| Molecular Biology and Evolutionary Biology Are Overlapping Fields of Study | p. 5 |
| An Overview of Evolutionary Biology | p. 7 |
| The History of Evolutionary Biology: Evolution and Genetics | p. 9 |
| A Brief Summary of Modern Genetics and Evolution | p. 9 |
| Evolution before Darwin | p. 10 |
| Charles Darwin | p. 16 |
| The Eclipse of Natural Selection | p. 18 |
| The Evolutionary Synthesis | p. 30 |
| The Origin of Molecular Biology | p. 37 |
| The Beginnings of Molecular Biology | p. 38 |
| Evolutionary and Molecular Biology: A New Synthesis? | p. 58 |
| Evidence for Evolution | p. 65 |
| Evidence for Evolution | p. 66 |
| Objections to Evolution | p. 76 |
| Science and Society | p. 81 |
| The Origin and Diversification of Life | p. 85 |
| The Origin of Life | p. 87 |
| When Did Life Begin on Earth? | p. 87 |
| How Did Life Begin on Earth? | p. 91 |
| The Last Universal Common Ancestor and the Tree of Life | p. 109 |
| Tracing Early Evolutionary History | p. 109 |
| Universal Homologies, LUCA, and the Tree of Life | p. 115 |
| Diversification of Bacteria and Archaea. I: Phylogeny and Biology | p. 137 |
| Introduction to the Bacteria and Archaea | p. 137 |
| Phylogenetic Diversification of Bacteria and Archaea | p. 142 |
| Biological Diversification of Bacteria and Archaea | p. 151 |
| Diversification of Bacteria and Archaea. II: Genetics and Genomics | p. 169 |
| The Nature of Archaeal and Bacterial Genomes | p. 169 |
| Lateral Transfer of DNA | p. 182 |
| The Origin and Diversification of Eukaryotes | p. 195 |
| Introduction to the Eukaryotes | p. 195 |
| Endosymbioses Have Played a Key Role in the Evolution of Eukaryotes | p. 202 |
| Structure and Evolution of the Nuclear Genome | p. 214 |
| Eukaryotic Diversification | p. 221 |
| Multicellularity and Development | p. 225 |
| How Multicellularity Happens | p. 225 |
| Division of Labor through Differentiation | p. 230 |
| Diversity of Body Plans | p. 238 |
| Genetics of Building a Body Plan | p. 244 |
| Diversification of Plants and Animals | p. 253 |
| Fossilization and Geological Time | p. 253 |
| The Flow of the Evolution of Life-forms | p. 254 |
| The Next 500 Million Years-Life Since the Cambrian Period | p. 272 |
| Patterns of Evolution | p. 280 |
| Evolution of Developmental Programs | p. 287 |
| Anterior-Posterior Patterning: Hox Gene Regulation of Development | p. 288 |
| Hox Genes Are Shown to Be Involved in Evolutionary Change | p. 293 |
| Skeletal Evolution in Sticklebacks | p. 307 |
| Evolution of Maize from Teosinte | p. 313 |
| Universality of Developmental Systems | p. 318 |
| Evolutionary Processes | p. 323 |
| Generation of Variation by Mutation and Recombination | p. 325 |
| Mutations and Mechanisms for Their Generation | p. 325 |
| Protection, Prevention, and Correction Mechanisms Limit the Number of Mutations Caused by DNA Damage and Replication Errors | p. 334 |
| Rates and Patterns of Mutations | p. 343 |
| Generation of Variation by Mixing: Sex and Lateral Gene Transfer | p. 349 |
| Variation in DNA and Proteins | p. 355 |
| Genetic Variation | p. 355 |
| Types of Genetic Variation | p. 367 |
| Variation in Genetically Complex Traits | p. 381 |
| Introduction to Quantitative Traits | p. 381 |
| Analyzing Quantitative Variation | p. 385 |
| The Genetic Basis of Quantitative Variation | p. 399 |
| Generation of Quantitative Variation | p. 409 |
| Random Genetic Drift | p. 413 |
| Evolution Is a Largely Random Process | p. 413 |
| Random Drift of Allele Frequencies | p. 415 |
| Coalescence | p. 420 |
| The Neutral Theory | p. 425 |
| Recombination and Random Drift | p. 427 |
| Population Structure | p. 439 |
| Gene Flow | p. 439 |
| Gene Flow Interacts with Other Evolutionary Forces | p. 444 |
| Genealogies in Structured Populations | p. 449 |
| Selection on Variation | p. 457 |
| The Nature of Selection | p. 457 |
| Selection on Quantitative Traits | p. 476 |
| Selection on Multiple Genes | p. 485 |
| The Interaction between Selection and Other Forces | p. 489 |
| Selection and Random Drift | p. 489 |
| Selection and Gene Flow | p. 496 |
| Balancing Selection | p. 505 |
| Mutation and Selection | p. 510 |
| Measuring Selection | p. 521 |
| Direct Measurement of Selection | p. 521 |
| Indirect Measurement | p. 530 |
| Selection on Linked Loci | p. 535 |
| Selection on Noncoding DNA | p. 542 |
| The Extent of Selection | p. 547 |
| Phenotypic Evolution | p. 555 |
| Evolutionary Optimization | p. 556 |
| Aging | p. 561 |
| Evolutionary Games | p. 567 |
| Sexual Selection | p. 573 |
| Conflict and Cooperation | p. 585 |
| Social Evolution | p. 586 |
| Conflict between Genes | p. 587 |
| Interactions between Relatives | p. 599 |
| Evolution of Cooperation | p. 611 |
| Species and Speciation | p. 619 |
| Defining Species | p. 620 |
| The Genetics of Speciation | p. 630 |
| Mechanisms of Speciation | p. 640 |
| The Geography of Speciation | p. 644 |
| Evolution of Genetic Systems | p. 657 |
| Studying the Evolution of Genetic Systems | p. 657 |
| Evolution of Mutation Rates | p. 659 |
| Evolution of Sex and Recombination | p. 663 |
| Consequences of Sex | p. 683 |
| Evolution of Evolvability | p. 689 |
| Evolution of Novelty | p. 695 |
| The Basic Features of Novelty | p. 696 |
| Changes in the Activity of Gene Products | p. 700 |
| Changes in Gene Regulation and Interactions within a Network: Targeting, Differentiation, and Development | p. 704 |
| Redundancy | p. 708 |
| Robustness, Modularity, and Compartmentalization | p. 711 |
| Acquiring New Functions from Other Species: Gene Transfer and Symbiosis | p. 717 |
| Natural Selection over Long Periods of Time Leads to the Origin of Novelty | p. 719 |
| Human Evolution | p. 725 |
| Human Evolutionary History | p. 727 |
| Placing Humans on the Tree of Life | p. 727 |
| The Evolution of Hominins | p. 731 |
| Genetics and Human Evolution | p. 741 |
| Genomics and Humanness | p. 749 |
| Current Issues in Human Evolution | p. 755 |
| The Genetic Basis of Disease | p. 755 |
| Understanding Human Nature | p. 769 |
| Glossary | p. 783 |
| Figure Credits | p. 802 |
| Index | p. 811 |
| Table of Contents provided by Ingram. All Rights Reserved. |
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