Principles of Molecular Oncology

, by Bronchud, Miguel H.; Foote, Maryann; Giaccone, Giuseppe, M.D.; Olopade, Olufunmilayo

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ISBN: 9781934115251 | 1934115258
Cover: Hardcover
Copyright: 12/4/2007

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Drawing on years of significant advances and developments, the editors of this third edition have thoroughly updated the highly praised first and second editions and added new chapters to reflect the knowledge emerging from research on genomics, proteomics, chemoprevention strategies, pharmacogenomics, new molecular targets, therapeutic monoclonal antibodies, and innovative cytotoxic and cytostatic small molecular-weight molecules.

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Foreword
Foreword to the Second Edition
Foreword to the First Edition
Foreword to the First Edition
Preface
Contributors
Color Plates
Selecting the Right Targets for Cancer Therapy	p. 1
Clinical Importance of Prognostic Factors: Moving from Scientifically Interesting to Clinically Useful	p. 27
Genetic Markers in Sporadic Tumors	p. 43
Genetic Markers in Breast Tumors with Hereditary Predisposition	p. 85
Circulating Tumor Markers	p. 107
Antibody-Based Proteomics Analysis of Tumor Cell Signaling Pathways	p. 117
Gene Expression Arrays for Pathway Analysis in Cancer Research	p. 135
Signaling Pathways in Cancer	p. 153
Estrogen Receptor Pathways and Breast Cancer	p. 189
Cyclin-Dependent Kinases and Their Regulators as Potential Targets for Anticancer Therapeutics	p. 207
Angiogenesis Switch Pathways	p. 239
Apoptosis Pathways and New Anticancer Agents	p. 257
Genomic Instability, DNA Repair Pathways and Cancer	p. 269
Epigenomics and Cancer	p. 281
Harnessing the Power of Immunity to Battle Cancer: Much Ado about Nothing or All's Well That Ends Well?	p. 293
Aurora Kinases: A New Target for Anticancer Drug Development	p. 307
Emerging Molecular Therapies: Drugs Interfering With Signal Transduction Pathways	p. 317
Suicide Gene Therapy	p. 367
Genotypes That Predict Toxicity and Genotypes That Predict Efficacy of Anticancer Drugs	p. 383
A Personal Account of the Chemoprevention of Breast Cancer: Possible or Not Possible?	p. 391
Abbreviations	p. 399
Trade Names/Generic Names	p. 403
Index	p. 405
Table of Contents provided by Blackwell. All Rights Reserved.

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Principles of Molecular Oncology

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Table of Contents

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