Paediatric Haematology and Oncology

Fully revised and updated for its second edition, Paediatric Haematology and Oncology provides an easily accessible source of information about all of the basic principles of childhood cancer and leukaemia, and detailed specialist knowledge on how to care for children with those conditions. Featuring new chapters on the biology of childhood leukaemia and central nervous system tumours, the book includes a greater focus on the rapidly expanding research in the biology and genetics of childhood malignancy, as well as new clinical treatments and more detail on various tumour types.

Logically split into 12 sections on different aspects of haematology and cancer to allow quick and easy reference, the book provides general principles of diagnosis and treatment, short- and long-term care, and oncological emergencies, before moving on to chapters on specific diseases. Normal values and useful websites are also included for reference.

Chapters have been expanded to feature more clinical images to aid in diagnosis and interpretation, making this second edition an invaluable companion for the trainee and consultant in paediatric haematology and oncology.

Simon Bailey, Consultant Paediatric Oncologist, and Honorary Professor of Paediatric Neuro-Oncology, Great North Children's Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, and Newcastle University,Rod Skinner, Consultant in Paediatric Oncology / Bone Marrow Transplantation, and
Honorary Professor of Childhood Cancer, Great North Children's Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, and Newcastle University

Professor Simon Bailey is a Consultant in Paediatric Oncology at the Great North Childrens Hospital, and an Honorary Professor of Paediatric Neuro-Oncology at the University of Newcastle upon Tyne. He specialises in brain tumours.

Professor Rod Skinner is a semi-retired paediatric and adolescent haemato-oncologist. He is the clinical lead for long-term follow-up of childhood and adolescent cancer and leukaemia.

Prior to semi-retirement, Professor Skinner was also clinical lead of the Paediatric Haematology Bone Marrow Transplant service and cared for children with acute leukaemia, aplastic anaemia and rare paediatric haematological malignancies.

Professor Skinner's clinical interests include long-term follow-up of individuals previously treated for childhood cancer or leukaemia, those who had bone marrow / stem cell transplants during childhood or adolescence, and childhood cancer survivorship.

1 Introduction to paediatric haematology and oncology
1. Epidemiology of childhood cancer, Professor Mark Pearce
2. Overview of biology and genetics of childhood cancer, Professor Deborah Tweddle
3. Paediatric oncology in the developing world, Professor Alan Davidson
2 General approaches to suspected cancer
4. Abdominal mass, Dr Fiona Herd
5. Initial diagnosis of brain tumours, Professor Simon Bailey
6. The bleeding or bruising child, Dr Geoff Shenton
7. Lymphadenopathy, Dr Sunita Dhir
8. Imaging of brain tumours, Dr Dipayan Mitra
9. Imaging of non-CNS tumours, Dr Claire Gowdy and Dr Leigh McDonald
3 Haematological and oncological emergencies
10. Haematological and oncological emergencies, Dr Simon Bomken, Dr Heather Lambert, Dr Anita Devlin, Dr Britta Vormoor, Dr Tina Biss, Professor Simon Bailey, and Professor Rod Skinner
4 General principles
11. Multimodality treatment, Professor Simon Bailey
12. Systemic anticancer drugs, Professor Rod Skinner and Ms Lynzie Middleton
13. Paediatric radiotherapy, Dr Joanne Lewis
14. Surgery, Dr Hany Gabra
15. Haemopoietic stem cell transplantation, Professor Rod Skinner and Dr Wing Roberts
16. Clinical trials, Sister Lisa Price
5 Supportive care
17. Infection, Professor Marieke Emonts, Dr Lucia Pareja-Cebrian, and Professor Rod Skinner
18. Blood transfusion, Dr Peter Carey
19. Pain, Sister Kelley Mellett and Amanda Gerrard
20. Other aspects of supportive care, Professor Simon Bailey, Professor Rod Skinner, Ms Fiona Court, Dr Heather Borrill, Mr Hany Gabra, Dr Peter Carey
6 Long term follow up
21. Long-term follow-up of childhood cancer survivors, Professor Rod Skinner
7 Benign haematological diseases
22. Haemoglobinopathies, Dr Peter Carey
23. Haemostasis and thrombosis, Dr Tina Biss
24. Bone marrow failure, Professor Rod Skinner
25. Other non-malignant causes of peripheral blood cytopenias, Dr Peter Carey
8 Malignant haematological diseases
26. Biology of childhood leukaemia, Dr Frederik Van Delft
27. Acute lymphoblastic leukaemia, Professor Josef Vormoor
28. Acute myeloid leukaemia, Dr Geoff Shenton, Dr Wing Roberts, and Professor Rod Skinner
29. Acute leukaemia of ambiguous lineage, Professor Rod Skinner
30. Myelodysplasia, Professor Rod Skinner
31. Chronic myeloid leukaemia and other chronic myeloproliferative neoplasms, Professor Rod Skinner
32. Lymphoma, Dr Simon Bomken
9 Solid tumours
33. Neuroblastoma, Professor Deborah Tweddle
34. Retinoblastoma, Dr Helen Jenkinson
35. Renal tumours, Dr Quentin Campbell-Hewson
36. Bone tumours, Dr Quentin Campbell-Hewson
37. Extracranial germ cell tumours, Dr Matthew Murray
38. Soft tissue sarcomas, Dr Gail Halliday
39. Liver tumours, Dr Gail Halliday
10 Central nervous system tumours
40. Biology of central nervous system tumours, Professor Steven Clifford
41. Central nervous system tumours, Professor Simon Bailey and Professor Jeannette Parkes
11 Other conditions
42. Histiocytosis, Dr Kevin Windebank
43. Rare tumours, Professor Bernadette Brennan
12 New treatment strategies
44. New treatment strategies, Professor Darren Hargrave