The DNA Provirus

Howard Temin's pioneering scientific achievements in elucidating the fundamentals of retroviruses laid the ground work for our present understanding of the molecular basis of both cancer and HIV. Few advances in contemporary molecular biology have been as significant or as controversial as Temin's initial proposal of the provirus hypothesis, which turned molecular biology's central dogma on its head. This book focuses on the significance of temin's science as well as on current areas of research which have been profoundly affected by his discoveries.